Is subjected to enzymatic digestion by alpha-amylase blood, which leads to the formation of oligo- and polysaccharides of various molecular weights. Has a from the blood of about 4 hours.Write trenbolone 250 mainly via the kidneys; 50% of the administered dose is excreted in the urine in less than 24 hours. Small amounts of drug deposited in the tissues temporarily, only 10% and continues to circulate in the blood serum. Sodium chloride is excreted mainly by the kidneys, and a small amount is excreted in the later through the skin.
1 .Lechenie and hypovolemia and shock prevention when:
- surgery (hemorrhagic shock)
- traumatic lesions (traumatic shock)
- infections (septic shock)
- burns (burn shock).
2.Ostraya normovolemic hemodilution to reduce the introduction of donor blood during surgery.
3 .Terapevticheskaya trenbolone 250 hemodilution.
Hypersensitivity (including starch), intracranial hypertension, arterial hypertension, intracranial hemorrhage, decompensated chronic heart failure, acute renal failure (oligo, anuria), severe bleeding diathesis, cardiogenic pulmonary edema, anticoagulation, coagulopathy, hyperhydration, hypervolemia, dehydration (if necessary correction of electrolyte metabolism), gipofibrinogenemia, severe thrombocytopenia, giperiatriemiya, hemodialysis.
Precautions: during lactation, compensated chronic heart failure, chronic renal failure, chronic liver disease, von Willebrand disease, hemorrhagic diathesis.
Use during pregnancy and lactation
Data on the use of trenbolone 250 in pregnant and lactating women do not. Use of the drug during pregnancy and lactation is possible only for health reasons.
Dosing and Administration
Dosages employed for the treatment and prevention of hypovolemia and shock.
The maximum daily dose:
6% solution 33 ml / kg / day (= 2,500 ml per 75 kg of body weight per day, or HEC = 2 g / kg / day).
10% solution 20 ml / kg / day (= 1,500 ml per 75 kg of body weight per day, or HEC = 2 g / kg / day).
Maximum infusion rate:
6% solution 20 ml / kg / hour (= 1500 ml per 75 kg of body weight per hour or 1,2 g HES / kg / hour).
10% solution 20 ml / kg / hour (= 1500 ml per 75 kg of body weight per hour or HES 2 g / kg / hour).
The doses used to reduce the amount of blood during surgery (acute normovolemic hemodilution).
For immediate preoperative substitution of his own blood to the simultaneous introduction of Hayes sr 6% in the ratio of 1: 1 (up to hematocrit
not less than 30%).
Sampling blood: 3.2 ml of 500 fold of their own blood.
Daily dose: 2-3 infusion of 500 mL of sterile-Hayes 6%.
Blood sampling trenbolone 250 rate of 1000 ml in 15-30 minutes.