Well absorbed after oral administration. Against the background of the inflammation of the meninges into the cerebrospinal fluid concentrations are equal to those in plasma. Rapidly and extensively metabolized mainly in the liver to pharmacologically inactive metabolites (amine derivative). Displayed in the kidney (65%), small tren 250 steroid amounts detected in the feces, where the therapeutic concentration is achieved against pathogens of intestinal infections
Indications for use
Dysentery, paratyphoid fever, giardiasis, food poisoning.
Pregnancy, lactation. Increased individual sensitivity to the nitrofurans group. End-stage chronic renal failure, deficiency of glucose-6-dehydrogenase, children under 3 years (for a given dosage form).Precautions Chronic renal failure, deficiency of glucose-6-phosphate dehydrogenase, liver and nervous system.
Dosing and Administration
Inside, after a meal. In dysentery, paratyphoid and nutritional diseases – 100-150 mg 4 times a day (but no more than 800 mg) tren 250 steroid for 5-10 days.
When giardiasis: adults – 100 mg 4 times a day, children – 10 mg / kg / day, distributing the daily dose into 3-4 receptions. The highest single dose for adults – 200 mg; daily – 800 mg.
Decreased appetite up to anorexia; nausea, vomiting; allergic reactions (skin rash, redness and itching of the skin, angioedema). With prolonged use – neuritis.
Overdose (intoxication) drug
Symptoms: acute toxic hepatitis, haematotoxicity, neurotoxicity (polyneuritis). Treatment: removal of drugs, drinking large amounts of fluid, symptomatic therapy, antihistamine.
The interaction with other drugs
furazolidone in combination with ethanol can result in the development disulfiramopodobnyh reactions, and therefore their simultaneous reception is not recommended.
Antidepressants, monoamine oxidase inhibitors, ephedrine, amphetamine, phenylephrine, tyramine mogutvyzvat tren 250 steroid sharp increase in blood pressure.
Increases blood oppression against the backdrop of chloramphenicol and ristomycin. It increases sensitivity to ethanol. Medicines, alkalizing urine, reduce the effect and acidifying – increase.
Aminoglycosides and tetracycline enhance the antimicrobial properties.
In the course of treatment should take precautions, like using a monoamine oxidase inhibitor, such as: exclusion from the diet foods containing tyramine: cheese, cream , beans, pickled herring, strong coffee. For the prevention of neuritis with prolonged use must be combined.
Form release Tablets. 50 mg.
10 tablets in a package Valium. On tren 250 steroid in banks orange glass.
At 800 contour bezgyachakova packages or 240 cans with an equal number of instructions for use are placed in a box made of cardboard (for hospitals).